Olfactory Dysfunction Predicts 5-Year Mortality in Older Adults
Loss of Smell as a Mortality Predictor

A study published in PLOS ONE found that olfactory dysfunction, or loss of smell, is a strong predictor of 5-year mortality in older adults. The research, which involved a nationally representative sample of U.S. adults aged 57-85, revealed that those with anosmia (complete loss of smell) had over three times the odds of death compared to those with normal olfactory function.
This increased risk was independent of other factors like age, gender, socioeconomic status, and common diseases. The study suggests that olfactory function may serve as an early indicator of broader physiological decline or cumulative environmental exposures, acting as a "bellwether" for the aging process.
The findings highlight the potential clinical utility of a simple olfactory test in identifying individuals at higher risk of mortality.